The Penicillin cocktail, a relatively recent addition to the world of mixed drinks, has quickly become a modern classic. Created in the early 2000s by bartender Sam Ross at the famed Milk & Honey bar in New York City, it has captured the attention of cocktail enthusiasts worldwide. This drink is not named for the antibiotic, but rather for its perceived soothing properties, like the old medicinal whisky and honey mixtures of the past. The cocktail is a sophisticated twist on the classic Whiskey Sour, incorporating a unique blend of flavors that have made it a staple in bars across the globe.
The Birth of a Modern Classic
Inspired by the Gold Rush
The Penicillin was inspired by another cocktail from Milk & Honey, the Gold Rush, which combines bourbon, lemon juice, and honey. Ross decided to experiment with this formula, swapping out the bourbon for blended Scotch whisky. He added a homemade honey-ginger syrup to introduce a sweet and spicy element and then topped it off with a float of smoky Islay single malt Scotch. This combination of ingredients created a complex yet balanced flavor profile.
A Global Phenomenon
Since its inception, the Penicillin has rapidly gained popularity, establishing itself as a must-try cocktail. Its unique blend of smoky, sweet, and tangy notes has appealed to a wide range of palates. The drink’s reputation has spread globally, with bartenders and cocktail lovers from every corner of the world embracing the Penicillin as a modern classic.
Deconstructing the Penicillin: Ingredients and Flavor Profile
Key Ingredients
The Penicillin cocktail is celebrated for its carefully balanced components:
- Blended Scotch Whisky: This forms the base of the cocktail, providing a smooth and malty foundation that complements the other flavors. Popular choices include Monkey Shoulder, Famous Grouse, and Johnnie Walker Black Label.
- Fresh Lemon Juice: The citrus element is vital, adding brightness and acidity that cuts through the sweetness of the syrup and the richness of the whisky.
- Honey-Ginger Syrup: This is a key component that distinguishes the Penicillin from other whisky-based cocktails. The syrup is made by combining honey, water, and fresh ginger, providing a sweet, warm, and spicy element.
- Islay Single Malt Scotch Whisky: This peaty whisky is used as a float, adding a layer of intense smokiness that is crucial to the drink’s overall flavor profile. Well-regarded options include Laphroaig 10 Year Old, Bowmore 12 Year Old, and Ardbeg 10 Year Old.
- Candied Ginger: This is used as a garnish and is meant to be enjoyed as a snack alongside the cocktail
A Symphony of Flavors
The flavor profile of the Penicillin is complex, with each sip offering a harmonious blend of smoky, sweet, and tangy flavors. It begins with a smoky and slightly peaty kick from the Islay Scotch, followed by a burst of fresh lemon. The honey-ginger syrup introduces a smooth, sweet, and spicy aftertaste that lingers on the palate. It’s a layered drink that is both approachable and memorable.
Crafting the Perfect Penicillin: A Step-by-Step Guide
Here’s how to make a Penicillin cocktail at home:
Ingredients:
- 2 ounces (60ml) Blended Scotch Whisky
- ¾ ounce (22.5ml) Freshly Squeezed Lemon Juice
- ¾ ounce (22.5ml) Honey-Ginger Syrup (see recipe below)
- ¼ ounce (7.5ml) Islay Single Malt Scotch Whisky
- Candied ginger, for garnish
Instructions:
- Prepare the Honey-Ginger Syrup: Combine 1 cup of honey with 1 cup of water and a 6-inch piece of peeled and thinly sliced fresh ginger in a saucepan. Simmer until the honey is dissolved and let it cool. Strain the syrup to remove the ginger slices. For a stronger ginger flavor, let the syrup infuse overnight.
- Combine Ingredients: In a cocktail shaker, add the blended Scotch, fresh lemon juice, and honey-ginger syrup.
- Shake Well: Fill the shaker with ice and shake vigorously until the mixture is well-chilled (about 15 seconds).
- Strain and Serve: Strain the mixture into a rocks glass filled with fresh ice, preferably a large ice cube or block ice.
- Add the Islay Scotch Float: Carefully pour the Islay single malt Scotch over the top of the drink so it forms a layer on top.
- Garnish: Add a piece of candied ginger as a garnish, which also makes a great snack.
Tips for Success
- Fresh Ingredients: Always use freshly squeezed lemon juice for the best flavor.
- Homemade Syrup: Making your own honey-ginger syrup will ensure a robust and balanced flavor.
- Quality Scotch: The quality of the Scotch will significantly affect the final taste. Choose a good blended Scotch for the base and a peaty Islay for the float.
- Don’t Overdo the Float: A small amount of Islay Scotch is all that’s needed to add a smoky aroma and depth. Using too much will overpower the other flavors.
Variations on a Classic
The Penicillin’s flexibility has led to numerous riffs and variations, allowing bartenders and enthusiasts to explore new flavor combinations:
Mezcal Penicillin
Swap the blended Scotch and Islay float for smoky mezcal for a variation that has a unique smoky taste.
Spritzy Penicillin
Add a splash of ginger beer or club soda to the mix for a lighter, more refreshing drink. This is a great option for those who prefer a less boozy version of the cocktail.
Hot Penicillin
Combine the ingredients in a heatproof mug with 1/2 cup of hot water for a warm and comforting version, perfect for colder weather.
Tropical Remedy
Replace the Islay Scotch with a peaty, tropical-flavored rum and swap out the honey-ginger syrup with a pineapple-infused honey syrup.
Berry Booster
Use a fruity bourbon or berry-infused whiskey instead of the scotch for a sweeter, more fruity variation.
Spiced Citrus Elixir
Opt for a spiced rum or cinnamon-infused whiskey for a warm and cozy twist, making it perfect for the colder months.
Food Pairings
The Penicillin’s complex flavor profile makes it a versatile partner to a variety of dishes. It complements savory and robust flavors, such as smoked meats like salmon or brisket. It pairs nicely with aged cheeses, where the drink’s complexity can match the rich flavors of the cheese. The honey-ginger notes of the cocktail also harmonize beautifully with dishes that have a touch of sweetness and spice, such as honey-glazed pork or ginger-infused Asian cuisine.
Why the Penicillin Endures
The Penicillin cocktail has proven itself to be more than just a trendy drink; it’s a testament to innovative mixology. Its unique combination of smoky, sweet, and tangy flavors, along with its intriguing history and adaptable nature, have secured its place as a modern classic. Whether enjoyed in a sophisticated cocktail bar or crafted at home, the Penicillin offers a sophisticated and well-balanced drinking experience that continues to delight cocktail enthusiasts worldwide. Its story is one of experimentation, balance, and the enduring appeal of a perfectly crafted drink.
